Tag Archives: 爱上海ZK

Artificial intelligence gears up to fight a future coronavirus

first_imgDisease outbreaks like the coronavirus often unfold too quickly for scientists to find a cure. But in the future, artificial intelligence could help researchers do a better job.While it’s probably too late for the fledgling technology to play a major role in the current epidemic, there’s hope for the next outbreaks. AI is good at combing through mounds of data to find connections that make it easier to determine what kinds of treatments could work or which experiments to pursue next.The question is what Big Data will come up with when it only gets meager scraps of information on a newly emerged illness like Covid-19, which first emerged late last year in China and has sickened more than 75,000 people in about two months.The fact that researchers managed to produce the gene sequencing of the new virus within weeks of the first reported cases is promising, since it shows there’s far more immediate data available now when outbreaks happen.Andrew Hopkins, chief executive officer of Oxford, England-based startup Exscientia Ltd. is among those working to help train artificial intelligence for drug discovery. He figures new treatments could go from conception to clinical testing in as little as 18 to 24 months within the next decade, thanks to AI.Exscientia designed a new compound for treating obsessive-compulsive disorder that’s ready to be tested in the lab after less than a year in the initial research phase. That’s about five times faster than average, according to the company.Cambridge-based Healx has a similar approach, but it uses machine learning to find new uses for existing drugs. Both companies feed their algorithms with information — gleaned from sources such as journals, biomedical databases and clinical trials — to help suggest new treatments for diseases.Human SupervisionThe two companies each use a team of human researchers to work alongside the AI to help guide the process. In Exscientia’s approach, dubbed the Centaur Chemist, drug designers help teach the algorithms strategies for searching for compounds. Healx puts the AI’s predictions to researchers who analyze the results and decide what to pursue.Neil Thompson, Healx’s chief science officer, said the technique could be deployed against an outbreak like the coronavirus as long as it had enough data on the new disease. Healx isn’t working on tackling the coronavirus or tweaking its technology for outbreaks, but it wouldn’t be a stretch.“We’re quite close,” Thompson said in an interview. “We wouldn’t need to change much about the AI algorithms we use. We look at matching drug properties to disease features.”One catch for all these technologies is clinical testing. Even drugs already safe for use to cure one ailment should be tested again before they’re prescribed for another. The process of showing they are safe and effective on a large number of people can take years before going to regulators for review.To be effective, AI-based drug developers would have to plan ahead of time, picking out a virus genome likely to cause problems in the future and targeting it when there are few incentives to do so.Read more about how drugmakers are hunting for ways to halt the coronavirus.Another obstacle is finding qualified staff.“It’s hard to find people who can operate at the intersection of AI and biology, and it’s difficult for big companies to make quick decisions on technology like this,” said Irina Haivas, a partner at venture capital firm Atomico and former surgeon who sits on the board of Healx. “It’s not enough to be an AI engineer, you have to understand and get into the applications of biology.”Topics :last_img read more

UNC looks for home win vs Wake Forest

first_img Associated Press TEAM LEADERS: Garrison Brooks has averaged 15.5 points and 8.4 rebounds to lead the charge for the Tar Heels. Complementing Brooks is Cole Anthony, who is accounting for 12.2 points per game. The Demon Deacons are led by Olivier Sarr, who is averaging 13.1 points and 8.5 rebounds.SPARKING THE OFFENSE: Anthony has had his hand in 45 percent of all North Carolina field goals over the last five games. The freshman guard has 36 field goals and 25 assists in those games.SCORING THRESHOLDS: North Carolina is 0-10 when its offense scores 65 points or fewer. Wake Forest is a perfect 6-0 when it holds opponents to 64 or fewer points.UNBEATEN WHEN: Wake Forest is a perfect 6-0 when it holds an opponent to 64 points or fewer. The Demon Deacons are 7-15 when opponents score more than 64.DID YOU KNOW: Wake Forest has attempted the sixth-most free throws in all of Division I. The Demon Deacons have averaged 24.4 free throws per game and 29 per game over their last five games. March 2, 2020 UNC looks for home win vs Wake Forestcenter_img Share This StoryFacebookTwitteremailPrintLinkedinRedditWake Forest (13-15, 6-12) vs. North Carolina (12-17, 5-13)Dean E. Smith Center, Chapel Hill, North Carolina; Tuesday, 7 p.m. ESTBOTTOM LINE: North Carolina looks for its fifth straight win over Wake Forest at Dean E. Smith Center. The last victory for the Demon Deacons at North Carolina was an 82-69 win on Jan. 20, 2010. ___For more AP college basketball coverage: https://apnews.com/Collegebasketball and http://twitter.com/AP_Top25___This was generated by Automated Insights, http://www.automatedinsights.com/ap, using data from STATS LLC, https://www.stats.comlast_img read more